New Data Shows Intradermal Administration of Mycoplasma Vaccines More Efficient Than Standard Methods

Data Presented at Fifth European Symposium of Porcine Health Management in Scotland 

BOXMEER, NETHERLANDS 11 JULY 2013 – MSD Animal Health (known as Merck Animal Health in the USA and Canada) hosted a symposium featuring data supporting the efficacy of intradermal administration of new mycoplasma vaccines compared to standard intramuscular vaccination in swine. The event was held prior to the start of the 5th European Symposium of Porcine Health Management in Edinburgh, Scotland on May 21 and May 22.

The double-blind, controlled study evaluated the local and systemic immune response induced by mycoplasma vaccines in swine. Vaccines were formulated to deliver the same amount of antigen content either intradermally with the IDAL vaccinator device (MSD Animal Health) or intramuscularly by standard syringe application. These treatments were compared to a control group given a placebo.

Based on Mycoplasma hyopneumoniae (M. hyopneumoniae) antibodies measured in blood and bronchoalveolar lavage (BAL), fluid samples, collected in vivo, intradermal administration appeared to stimulate the immune system at least as efficiently as the intramuscular administration, if not better. In addition, the data supported that intradermal administration engages a more efficient stimulation of the mucosal and cell mediated immunity.

M. hyopneumoniae causes significant reduction in the growing weight of pigs and treatment, once infected, is limited to antibiotics that may not be effective.

“This highly contagious chronic respiratory disease in swine can have severe economic impact for farmers,” explains Dr. Rika Jolie, Director, Scientific Marketing Affairs, MSD Animal Health. “An effective means of vaccination against this disease can help farmers with the management of herd health.”

Intradermal vaccination is an animal-friendly option, is less painful and stressful for the pigs at time of application, and has  better hygiene and less potential for spread of disease. The intradermal application also provides a safer means of administering the vaccine with no implications to the quality of the meat.

About MSD Animal Health
Today’s Merck is a global healthcare leader working to help the world be well. MSD Animal Health, known as Merck Animal Health in the United States and Canada, is the global animal health business unit of Merck. MSD Animal Health offers veterinarians, farmers, pet owners and governments one of the widest range of veterinary pharmaceuticals, vaccines and health management solutions and services. MSD Animal Health is dedicated to preserving and improving the health, well-being and performance of animals. It invests extensively in dynamic and comprehensive R&D resources and a modern, global supply chain. MSD Animal Health is present in more than 50 countries, while its products are available in some 150 markets. For more information, visit

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